Recombinant Vaccine–Derived Poliovirus in Madagascar
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چکیده
منابع مشابه
Recombinant Vaccine–Derived Poliovirus in Madagascar
TsCysti was exclusively endemic (2). The contaminated areas in Irian Jaya have increased from the central area (Paniai), to the east (Jayawijaya) (3), and then to the west (Manokwari), where 54 TsCysti cases have been reported (Papua Province Health Office Services, 1997, unpub. data). We wanted to know if taeniasis/cysticercosis had been introduced into the eastern half of New Guinea Island, c...
متن کاملReemergence of recombinant vaccine-derived poliovirus outbreak in Madagascar.
BACKGROUND After the 2001-2002 poliomyelitis outbreak due to recombinant vaccine-derived polioviruses (VDPVs) in the Toliara province of Madagascar, another outbreak reoccurred in the same province in 2005. METHODS We conducted epidemiological and virological investigations for each polio case patient and for their contacts. RESULTS From May to August 2005, a total of 5 cases of acute flacc...
متن کاملAssessment of poliovirus antibody seroprevalence in high risk areas for vaccine derived poliovirus transmission in Madagascar
Background Vaccine-derived polioviruses (VDPV) outbreaks typically occur in areas of low poliovirus immunity. Madagascar successfully eradicated wild poliovirus in 1997; however, multiple VDPV outbreaks have occurred since then, and numerous vaccination campaigns have been carried out to control the VDPV outbreaks. We conducted a survey of poliovirus neutralizing antibodies among Malagasy child...
متن کاملSelective isolation of poliovirus in recombinant murine cell line expressing the human poliovirus receptor gene.
Sixty-eight laboratory strains representing 49 enterovirus, 10 adenovirus, and 3 reovirus serotypes were inoculated in a recombinant murine cell line expressing the human poliovirus receptor gene (L alpha cells). Only polioviruses caused cytopathic effect over a 10-day period. Likewise, only polioviruses were isolated, by use of L alpha cells, from 168 fecal specimens from children from develop...
متن کاملReemergence of Recombinant Vaccine–derived Polioviruses in Healthy Children, Madagascar
To the Editor: Poliomyelitis outbreaks caused by pathogenic vaccine-derived polioviruses (VDPVs) are primarily a result of low polio vaccine coverage. Low coverage enables interhuman circulation of polioviruses (PVs) from the oral polio vaccine (OPV), and it enables genetic drift of the viruses and their subsequent reversion to neurovirulent phenotypes (1). Polio outbreaks associated with type ...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2003
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid0907.020692